CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components

Motile cilia can beat with distinct patterns, but how motility variations are regulated remain obscure. Here, we have studied the role of the coiled-coil protein CFAP53 in the motility of different cilia-types in the mouse. While node (9+0) cilia of Cfap53 mutants were immotile, tracheal and ependym...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Ide, Takahiro, Twan, Wang Kyaw, Lu, Hao, Ikawa, Yayoi, Lim, Lin-Xenia, Henninger, Nicole, Nishimura, Hiromi, Takaoka, Katsuyoshi, Narasimhan, Vijay, Yan, Xiumin, Shiratori, Hidetaka, Roy, Sudipto, Hamada, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817014/
https://ncbi.nlm.nih.gov/pubmed/33347437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009232
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