CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components

Motile cilia can beat with distinct patterns, but how motility variations are regulated remain obscure. Here, we have studied the role of the coiled-coil protein CFAP53 in the motility of different cilia-types in the mouse. While node (9+0) cilia of Cfap53 mutants were immotile, tracheal and ependym...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS Genet
المؤلفون الرئيسيون: Ide, Takahiro, Twan, Wang Kyaw, Lu, Hao, Ikawa, Yayoi, Lim, Lin-Xenia, Henninger, Nicole, Nishimura, Hiromi, Takaoka, Katsuyoshi, Narasimhan, Vijay, Yan, Xiumin, Shiratori, Hidetaka, Roy, Sudipto, Hamada, Hiroshi
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2020
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817014/
https://ncbi.nlm.nih.gov/pubmed/33347437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009232
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