CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components

Motile cilia can beat with distinct patterns, but how motility variations are regulated remain obscure. Here, we have studied the role of the coiled-coil protein CFAP53 in the motility of different cilia-types in the mouse. While node (9+0) cilia of Cfap53 mutants were immotile, tracheal and ependym...

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Pubblicato in:PLoS Genet
Autori principali: Ide, Takahiro, Twan, Wang Kyaw, Lu, Hao, Ikawa, Yayoi, Lim, Lin-Xenia, Henninger, Nicole, Nishimura, Hiromi, Takaoka, Katsuyoshi, Narasimhan, Vijay, Yan, Xiumin, Shiratori, Hidetaka, Roy, Sudipto, Hamada, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817014/
https://ncbi.nlm.nih.gov/pubmed/33347437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009232
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