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Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm
Axonemal dynein complexes are preassembled in the cytoplasm before their transport to cilia, but the mechanism of this process remains unclear. We now show that mice lacking Pih1d3, a PIH1 domain–containing protein, develop normally but manifest male sterility. Pih1d3(−/−) sperm were immotile and fr...
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| Hlavní autoři: | , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897177/ https://ncbi.nlm.nih.gov/pubmed/24421334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201304076 |
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