Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue

Gene therapeutic approaches to aortic diseases require efficient vectors and delivery systems for transduction of endothelial cells (ECs) and smooth muscle cells (SMCs). Here, we developed a novel strategy to efficiently deliver a previously described vascular-specific adeno-associated viral (AAV) v...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Mol Ther Methods Clin Dev
Huvudupphovsmän: Remes, Anca, Basha, Dima Ibrahim, Puehler, Thomas, Borowski, Christopher, Hille, Susanne, Kummer, Laura, Wagner, Andreas H., Hecker, Markus, Soethoff, Jasmin, Lutter, Georg, Frank, Derk, Arif, Rawa, Frey, Norbert, Zaradzki, Marcin, Müller, Oliver J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Gene & Cell Therapy 2021
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973147/
https://ncbi.nlm.nih.gov/pubmed/33768132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.02.017
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk