Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue

Gene therapeutic approaches to aortic diseases require efficient vectors and delivery systems for transduction of endothelial cells (ECs) and smooth muscle cells (SMCs). Here, we developed a novel strategy to efficiently deliver a previously described vascular-specific adeno-associated viral (AAV) v...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther Methods Clin Dev
Hoofdauteurs: Remes, Anca, Basha, Dima Ibrahim, Puehler, Thomas, Borowski, Christopher, Hille, Susanne, Kummer, Laura, Wagner, Andreas H., Hecker, Markus, Soethoff, Jasmin, Lutter, Georg, Frank, Derk, Arif, Rawa, Frey, Norbert, Zaradzki, Marcin, Müller, Oliver J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2021
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973147/
https://ncbi.nlm.nih.gov/pubmed/33768132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.02.017
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