Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue

Gene therapeutic approaches to aortic diseases require efficient vectors and delivery systems for transduction of endothelial cells (ECs) and smooth muscle cells (SMCs). Here, we developed a novel strategy to efficiently deliver a previously described vascular-specific adeno-associated viral (AAV) v...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Methods Clin Dev
Egile Nagusiak: Remes, Anca, Basha, Dima Ibrahim, Puehler, Thomas, Borowski, Christopher, Hille, Susanne, Kummer, Laura, Wagner, Andreas H., Hecker, Markus, Soethoff, Jasmin, Lutter, Georg, Frank, Derk, Arif, Rawa, Frey, Norbert, Zaradzki, Marcin, Müller, Oliver J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2021
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973147/
https://ncbi.nlm.nih.gov/pubmed/33768132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.02.017
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