AAV-mediated expression of NFAT decoy oligonucleotides protects from cardiac hypertrophy and heart failure

Previous studies have underlined the substantial role of nuclear factor of activated T cells (NFAT) in hypertension-induced myocardial hypertrophy ultimately leading to heart failure. Here, we aimed at neutralizing four members of the NFAT family of transcription factors as a therapeutic strategy fo...

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Bibliografiske detaljer
Udgivet i:Basic Res Cardiol
Main Authors: Remes, Anca, Wagner, Andreas H., Schmiedel, Nesrin, Heckmann, Markus, Ruf, Theresa, Ding, Lin, Jungmann, Andreas, Senger, Frauke, Katus, Hugo A., Ullrich, Nina D., Frey, Norbert, Hecker, Markus, Müller, Oliver J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2021
Fag:
Original Contribution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178147/
https://ncbi.nlm.nih.gov/pubmed/34089101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-021-00880-w
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