Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

Antibodies with heavy chains that derive from the VH1-2 gene constitute some of the most potent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing antibodies yet identified. To provide insight into whether these genetic similarities inform common modes of recognition, we deter...

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Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Rapp, Micah, Guo, Yicheng, Reddem, Eswar R., Yu, Jian, Liu, Lihong, Wang, Pengfei, Cerutti, Gabriele, Katsamba, Phinikoula, Bimela, Jude S., Bahna, Fabiana A., Mannepalli, Seetha M., Zhang, Baoshan, Kwong, Peter D., Huang, Yaoxing, Ho, David D., Shapiro, Lawrence, Sheng, Zizhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Author(s). 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972811/
https://ncbi.nlm.nih.gov/pubmed/33794145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108950
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