Structural Basis for Accommodation of Emerging B.1.351 and B.1.1.7 Variants by Two Potent SARS-CoV-2 Neutralizing Antibodies

Emerging SARS-CoV-2 strains, B.1.1.7 and B.1.351, from the UK and South Africa, respectively show decreased neutralization by monoclonal antibodies and convalescent or vaccinee sera raised against the original wild-type virus, and are thus of clinical concern. However, the neutralization potency of...

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Udgivet i:bioRxiv
Main Authors: Cerutti, Gabriele, Rapp, Micah, Guo, Yicheng, Bahna, Fabiana, Bimela, Jude, Reddem, Eswar R., Yu, Jian, Wang, Pengfei, Liu, Lihong, Huang, Yaoxing, Ho, David D., Kwong, Peter D., Sheng, Zizhang, Shapiro, Lawrence
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924265/
https://ncbi.nlm.nih.gov/pubmed/33655245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.21.432168
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