DIP/Dpr interactions and the evolutionary design of specificity in protein families

Differential binding affinities among closely related protein family members underlie many biological phenomena, including cell-cell recognition. Drosophila DIP and Dpr proteins mediate neuronal targeting in the fly through highly specific protein-protein interactions. We show here that DIPs/Dprs se...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Sergeeva, Alina P., Katsamba, Phinikoula S., Cosmanescu, Filip, Brewer, Joshua J., Ahlsen, Goran, Mannepalli, Seetha, Shapiro, Lawrence, Honig, Barry
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195491/
https://ncbi.nlm.nih.gov/pubmed/32358559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15981-8
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