tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast

Protein synthesis rate and accuracy are tightly controlled by the cell and are essential for proteome homoeostasis (proteostasis); however, the full picture of how mRNA translational factors maintain protein synthesis accuracy and co-translational protein folding are far from being fully understood....

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Tavares, Joana F, Davis, Nick K., Poim, Ana, Reis, Andreia, Kellner, Stefanie, Sousa, Inês, Soares, Ana R., Moura, Gabriela M R, Dedon, Peter C, Santos, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971265/
https://ncbi.nlm.nih.gov/pubmed/32893724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1819671
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