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Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine

Translational quality control is monitored at several steps, including substrate selection by aminoacyl-tRNA synthetases (aaRSs), and discrimination of aminoacyl-tRNAs by elongation factor Tu (EF-Tu) and the ribosome. Phenylalanyl-tRNA synthetase (PheRS) misactivates Tyr but is able to correct the m...

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Bibliografski detalji
Glavni autori: Ling, Jiqiang, Yadavalli, Srujana S., Ibba, Michael
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040089/
https://ncbi.nlm.nih.gov/pubmed/17804641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.684107
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