The Yeast PNC1 Longevity Gene Is Up-Regulated by mRNA Mistranslation

Translation fidelity is critical for protein synthesis and to ensure correct cell functioning. Mutations in the protein synthesis machinery or environmental factors that increase synthesis of mistranslated proteins result in cell death and degeneration and are associated with neurodegenerative disea...

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Detalhes bibliográficos
Main Authors: Silva, Raquel M., Duarte, Iven C. N., Paredes, João A., Lima-Costa, Tatiana, Perrot, Michel, Boucherie, Hélian, Goodfellow, Brian J., Gomes, Ana C., Mateus, Denisa D., Moura, Gabriela R., Santos, Manuel A. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667667/
https://ncbi.nlm.nih.gov/pubmed/19381334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005212
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