Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence

BACKGROUND: In multiple sclerosis loss of myelin and oligodendrocytes impairs saltatory signal transduction and leads to neuronal loss and functional deficits. Limited capacity of oligodendroglial precursor cells to differentiate into mature cells is the main reason for inefficient myelin repair in...

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Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Manousi, Anastasia, Göttle, Peter, Reiche, Laura, Cui, Qiao-Ling, Healy, Luke M., Akkermann, Rainer, Gruchot, Joel, Schira-Heinen, Jessica, Antel, Jack P., Hartung, Hans-Peter, Küry, Patrick
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970057/
https://ncbi.nlm.nih.gov/pubmed/33714029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103276
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