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Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence
BACKGROUND: In multiple sclerosis loss of myelin and oligodendrocytes impairs saltatory signal transduction and leads to neuronal loss and functional deficits. Limited capacity of oligodendroglial precursor cells to differentiate into mature cells is the main reason for inefficient myelin repair in...
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| Publicat a: | EBioMedicine |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7970057/ https://ncbi.nlm.nih.gov/pubmed/33714029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103276 |
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