Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence

BACKGROUND: In multiple sclerosis loss of myelin and oligodendrocytes impairs saltatory signal transduction and leads to neuronal loss and functional deficits. Limited capacity of oligodendroglial precursor cells to differentiate into mature cells is the main reason for inefficient myelin repair in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EBioMedicine
Prif Awduron: Manousi, Anastasia, Göttle, Peter, Reiche, Laura, Cui, Qiao-Ling, Healy, Luke M., Akkermann, Rainer, Gruchot, Joel, Schira-Heinen, Jessica, Antel, Jack P., Hartung, Hans-Peter, Küry, Patrick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2021
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970057/
https://ncbi.nlm.nih.gov/pubmed/33714029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103276
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