Sildenafil Inhibits Myelin Expression and Myelination of Oligodendroglial Precursor Cells

Phosphodiesterases (PDEs) have previously been implicated in oligodendrocyte maturation and myelination of central nervous system axons. Sildenafil citrate is a phosphodiesterase inhibitor known to block PDE5, which also reduces inflammation in the experimental autoimmune encephalomyelitis demyelina...

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Dades bibliogràfiques
Publicat a:ASN Neuro
Autors principals: Muñoz-Esquivel, Jonathan, Göttle, Peter, Aguirre-Cruz, Lucinda, Flores-Rivera, José, Corona, Teresa, Reyes-Terán, Gustavo, Küry, Patrick, Torres, Klintsy J.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2019
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410393/
https://ncbi.nlm.nih.gov/pubmed/30849920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091419832444
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