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A Different hIAPP Polymorph Is Observed in Human Serum Than in Aqueous Buffer: Demonstration of a New Method for Studying Amyloid Fibril Structure Using Infrared Spectroscopy

There is enormous interest in measuring amyloid fibril structures, but most structural studies measure fibril formation in vitro using aqueous buffer. Ideally, one would like to measure fibril structure and mechanism under more physiological conditions. Toward this end, we have developed a method fo...

詳細記述

保存先:
書誌詳細
出版年:J Phys Chem Lett
主要な著者: Fields, Caitlyn R., Dicke, Sidney S., Petti, Megan K., Zanni, Martin T., Lomont, Justin P.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968077/
https://ncbi.nlm.nih.gov/pubmed/32706257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.0c01345
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