ANO1 Expression Orchestrates p27Kip1/MCL1-Mediated Signaling in Head and Neck Squamous Cell Carcinoma

SIMPLE SUMMARY: Our aim was to elucidate the molecular mechanisms of how ANO1 contributes to oncogenic processes in squamous cell carcinoma of the head and neck (HNSCC). We explored transcriptional programs influenced by ANO1 knockdown in patient-derived UT-SCC cell lines with 11q13 amplification an...

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Pubblicato in:Cancers (Basel)
Autori principali: Filippou, Artemis, Pehkonen, Henna, Karhemo, Piia-Riitta, Väänänen, Juho, Nieminen, Anni I., Klefström, Juha, Grénman, Reidar, Mäkitie, Antti A., Joensuu, Heikki, Monni, Outi
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967175/
https://ncbi.nlm.nih.gov/pubmed/33803266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051170
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