Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

In vitro cancer drug testing carries a low predictive value. We developed the human leiomyoma–derived matrix “Myogel” to better mimic the human tumor microenvironment (TME). We hypothesized that Myogel could provide an appropriate microenvironment for cancer cells, thereby allowing more in vivo–rele...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Tuomainen, Katja, Al-Samadi, Ahmed, Potdar, Swapnil, Turunen, Laura, Turunen, Minna, Karhemo, Piia-Riitta, Bergman, Paula, Risteli, Maija, Åström, Pirjo, Tiikkaja, Riia, Grenman, Reidar, Wennerberg, Krister, Monni, Outi, Salo, Tuula
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017272/
https://ncbi.nlm.nih.gov/pubmed/31905951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010092
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