Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

In vitro cancer drug testing carries a low predictive value. We developed the human leiomyoma–derived matrix “Myogel” to better mimic the human tumor microenvironment (TME). We hypothesized that Myogel could provide an appropriate microenvironment for cancer cells, thereby allowing more in vivo–rele...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Tuomainen, Katja, Al-Samadi, Ahmed, Potdar, Swapnil, Turunen, Laura, Turunen, Minna, Karhemo, Piia-Riitta, Bergman, Paula, Risteli, Maija, Åström, Pirjo, Tiikkaja, Riia, Grenman, Reidar, Wennerberg, Krister, Monni, Outi, Salo, Tuula
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017272/
https://ncbi.nlm.nih.gov/pubmed/31905951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010092
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