Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

In vitro cancer drug testing carries a low predictive value. We developed the human leiomyoma–derived matrix “Myogel” to better mimic the human tumor microenvironment (TME). We hypothesized that Myogel could provide an appropriate microenvironment for cancer cells, thereby allowing more in vivo–rele...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Tuomainen, Katja, Al-Samadi, Ahmed, Potdar, Swapnil, Turunen, Laura, Turunen, Minna, Karhemo, Piia-Riitta, Bergman, Paula, Risteli, Maija, Åström, Pirjo, Tiikkaja, Riia, Grenman, Reidar, Wennerberg, Krister, Monni, Outi, Salo, Tuula
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017272/
https://ncbi.nlm.nih.gov/pubmed/31905951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010092
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