Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

Proteases are among the largest protein families and critical regulators of biochemical processes like apoptosis and blood coagulation. Knowledge of proteases has been expanded by the development of proteomic approaches, however, technology for multiplexed screening of proteases within native enviro...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Uliana, Federico, Vizovišek, Matej, Acquasaliente, Laura, Ciuffa, Rodolfo, Fossati, Andrea, Frommelt, Fabian, Goetze, Sandra, Wollscheid, Bernd, Gstaiger, Matthias, De Filippis, Vincenzo, auf dem Keller, Ulrich, Aebersold, Ruedi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966775/
https://ncbi.nlm.nih.gov/pubmed/33727531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21754-8
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