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Sites of chromosomal instability in the context of nuclear architecture and function

Chromosomal fragile sites are described as areas within the tightly packed mitotic chromatin that appear as breaks or gaps mostly tracing back to a loosened structure and not a real nicked break within the DNA molecule. Most facts about fragile sites result from studies in mitotic cells, mainly duri...

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Vydáno v:Cell Mol Life Sci
Hlavní autoři: Pentzold, Constanze, Kokal, Miriam, Pentzold, Stefan, Weise, Anja
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966619/
https://ncbi.nlm.nih.gov/pubmed/33219838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03698-2
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