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Sites of chromosomal instability in the context of nuclear architecture and function

Chromosomal fragile sites are described as areas within the tightly packed mitotic chromatin that appear as breaks or gaps mostly tracing back to a loosened structure and not a real nicked break within the DNA molecule. Most facts about fragile sites result from studies in mitotic cells, mainly duri...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Pentzold, Constanze, Kokal, Miriam, Pentzold, Stefan, Weise, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966619/
https://ncbi.nlm.nih.gov/pubmed/33219838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03698-2
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