A Mechanistic In Vivo/Ex Vivo Pharmacokinetic‐Pharmacodynamic Model of Tenofovir for HIV Prevention

Defining tissue and plasma‐specific prophylactic drug concentrations is central to pre‐exposure prophylaxis product development for sexual transmission of HIV‐1. Pharmacokinetic (PK) data from study RMP‐02/MTN‐006 comparing single dose oral tenofovir disoproxil fumarate with single and multiple dose...

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Sparad:
Bibliografiska uppgifter
I publikationen:CPT Pharmacometrics Syst Pharmacol
Huvudupphovsmän: Jayachandran, Priya, Garcia-Cremades, Maria, Vučićević, Katarina, Bumpus, Namandjé N., Anton, Peter, Hendrix, Craig, Savić, Radojka
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7965838/
https://ncbi.nlm.nih.gov/pubmed/33547874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12583
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