RMP-02/MTN-006: A Phase 1 Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Tenofovir 1% Gel Compared with Oral Tenofovir Disoproxil Fumarate

This study was designed to assess the safety, acceptability, pharmacokinetic (PK), and pharmacodynamic (PD) responses to rectal administration of tenofovir (TFV) 1% vaginally formulated gel and oral tenofovir disoproxil fumarate (TDF). This study was designed as a phase 1, randomized, two-site (Unit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Anton, Peter A., Cranston, Ross D., Kashuba, Angela, Hendrix, Craig W., Bumpus, Namandjé N., Richardson-Harman, Nicola, Elliott, Julie, Janocko, Laura, Khanukhova, Elena, Dennis, Robert, Cumberland, William G., Ju, Chuan, Carballo-Diéguez, Alex, Mauck, Christine, McGowan, Ian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2012
Pynciau:
Clinical Trials/Clinical Studies
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484811/
https://ncbi.nlm.nih.gov/pubmed/22943559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0262
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