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Ibrutinib modulates Aβ/tau pathology, neuroinflammation, and cognitive function in mouse models of Alzheimer's disease

We previously demonstrated that ibrutinib modulates LPS‐induced neuroinflammation in vitro and in vivo, but its effects on the pathology of Alzheimer's disease (AD) and cognitive function have not been investigated. Here, we investigated the effects of ibrutinib in two mouse models of AD. In 5x...

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Detaylı Bibliyografya
Yayımlandı:Aging Cell
Asıl Yazarlar: Lee, Hyun‐ju, Jeon, Seong Gak, Kim, Jieun, Kang, Ri Jin, Kim, Seong‐Min, Han, Kyung‐Min, Park, HyunHee, Kim, Ki‐taek, Sung, You Me, Nam, Hye Yeon, Koh, Young Ho, Song, Minseok, Suk, Kyoungho, Hoe, Hyang‐Sook
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963331/
https://ncbi.nlm.nih.gov/pubmed/33709472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13332
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