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The VEGF inhibitor vatalanib regulates AD pathology in 5xFAD mice
Alzheimer’s disease (AD) is a highly prevalent neurodegenerative disease characterized by Aβ accumulation and tau hyperphosphorylation. Epidemiological evidence for a negative correlation between cancer and AD has led to the proposed use of tyrosine kinase inhibitors (TKIs) such as dasatinib and mas...
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| Опубликовано в: : | Mol Brain |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519542/ https://ncbi.nlm.nih.gov/pubmed/32977842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00673-7 |
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