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The VEGF inhibitor vatalanib regulates AD pathology in 5xFAD mice

Alzheimer’s disease (AD) is a highly prevalent neurodegenerative disease characterized by Aβ accumulation and tau hyperphosphorylation. Epidemiological evidence for a negative correlation between cancer and AD has led to the proposed use of tyrosine kinase inhibitors (TKIs) such as dasatinib and mas...

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Publicado en:Mol Brain
Autores principales: Jeon, Seong Gak, Lee, Hyun-ju, Park, HyunHee, Han, Kyung-Min, Hoe, Hyang-Sook
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519542/
https://ncbi.nlm.nih.gov/pubmed/32977842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00673-7
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