Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

AIMS: Diastolic dysfunction (DD) is common among hypertrophic cardiomyopathy (HCM) patients, causing major morbidity and mortality. However, its cellular mechanisms are not fully understood, and presently there is no effective treatment. Patient-specific induced pluripotent stem cell-derived cardiom...

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Bibliografiske detaljer
Udgivet i:Eur Heart J
Main Authors: Wu, Haodi, Yang, Huaxiao, Rhee, June-Wha, Zhang, Joe Z, Lam, Chi Keung, Sallam, Karim, Chang, Alex C Y, Ma, Ning, Lee, Jaecheol, Zhang, Hao, Blau, Helen M, Bers, Donald M, Wu, Joseph C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Basic Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963137/
https://ncbi.nlm.nih.gov/pubmed/31219556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz326
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