Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Excessive iron accumulation in the heart causes iron overload cardiomyopathy (IOC) which initially presents as diastolic dysfunction and arrhythmia but progresses to systolic dysfunction and end-stage heart failure when left untreated. However, the mechanisms of iron-related cardiac injury and how i...

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Publicado no:Cell Rep
Main Authors: Rhee, June-Wha, Yi, Hyoju, Thomas, Dilip, Lam, Chi Keung, Belbachir, Nadjet, Tian, Lei, Qin, Xulei, Malisa, Jessica, Lau, Edward, Paik, David T., Kim, Youngkyun, Choi, Beatrice SeungHye, Sayed, Nazish, Sallam, Karim, Liao, Ronglih, Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553857/
https://ncbi.nlm.nih.gov/pubmed/32668256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107886
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