Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

AIMS: Diastolic dysfunction (DD) is common among hypertrophic cardiomyopathy (HCM) patients, causing major morbidity and mortality. However, its cellular mechanisms are not fully understood, and presently there is no effective treatment. Patient-specific induced pluripotent stem cell-derived cardiom...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Wu, Haodi, Yang, Huaxiao, Rhee, June-Wha, Zhang, Joe Z, Lam, Chi Keung, Sallam, Karim, Chang, Alex C Y, Ma, Ning, Lee, Jaecheol, Zhang, Hao, Blau, Helen M, Bers, Donald M, Wu, Joseph C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963137/
https://ncbi.nlm.nih.gov/pubmed/31219556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz326
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