Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

AIMS: Diastolic dysfunction (DD) is common among hypertrophic cardiomyopathy (HCM) patients, causing major morbidity and mortality. However, its cellular mechanisms are not fully understood, and presently there is no effective treatment. Patient-specific induced pluripotent stem cell-derived cardiom...

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Detalles Bibliográficos
Publicado en:Eur Heart J
Main Authors: Wu, Haodi, Yang, Huaxiao, Rhee, June-Wha, Zhang, Joe Z, Lam, Chi Keung, Sallam, Karim, Chang, Alex C Y, Ma, Ning, Lee, Jaecheol, Zhang, Hao, Blau, Helen M, Bers, Donald M, Wu, Joseph C
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Basic Science
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963137/
https://ncbi.nlm.nih.gov/pubmed/31219556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz326
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