Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

AIMS: Diastolic dysfunction (DD) is common among hypertrophic cardiomyopathy (HCM) patients, causing major morbidity and mortality. However, its cellular mechanisms are not fully understood, and presently there is no effective treatment. Patient-specific induced pluripotent stem cell-derived cardiom...

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Dettagli Bibliografici
Pubblicato in:Eur Heart J
Autori principali: Wu, Haodi, Yang, Huaxiao, Rhee, June-Wha, Zhang, Joe Z, Lam, Chi Keung, Sallam, Karim, Chang, Alex C Y, Ma, Ning, Lee, Jaecheol, Zhang, Hao, Blau, Helen M, Bers, Donald M, Wu, Joseph C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963137/
https://ncbi.nlm.nih.gov/pubmed/31219556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz326
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