Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

AIMS: Diastolic dysfunction (DD) is common among hypertrophic cardiomyopathy (HCM) patients, causing major morbidity and mortality. However, its cellular mechanisms are not fully understood, and presently there is no effective treatment. Patient-specific induced pluripotent stem cell-derived cardiom...

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Bibliografiska uppgifter
I publikationen:Eur Heart J
Huvudupphovsmän: Wu, Haodi, Yang, Huaxiao, Rhee, June-Wha, Zhang, Joe Z, Lam, Chi Keung, Sallam, Karim, Chang, Alex C Y, Ma, Ning, Lee, Jaecheol, Zhang, Hao, Blau, Helen M, Bers, Donald M, Wu, Joseph C
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Basic Science
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963137/
https://ncbi.nlm.nih.gov/pubmed/31219556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz326
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