Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer’s disease

SORL1 is strongly associated with both sporadic and familial forms of Alzheimer’s disease (AD), but a lack of information about alternatively spliced transcripts currently limits our understanding of the role of SORL1 in AD. Here, we describe a SORL1 transcript (SORL1-38b) characterized by inclusion...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Monti, Giulia, Kjolby, Mads, Jensen, Anne Mette G., Allen, Mariet, Reiche, Juliane, Møller, Peter L., Comaposada-Baró, Raquel, Zolkowski, Bartlomiej E., Vieira, Cármen, Jørgensen, Margarita Melnikova, Holm, Ida E., Valdmanis, Paul N., Wellner, Niels, Vægter, Christian B., Lincoln, Sarah J., Nykjær, Anders, Ertekin-Taner, Nilüfer, Young, Jessica E., Nyegaard, Mette, Andersen, Olav M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962264/
https://ncbi.nlm.nih.gov/pubmed/33726851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01140-7
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