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Genetics of Alzheimer disease in the pre- and post-GWAS era

Since the 1990s, the genetics of Alzheimer disease (AD) has been an active area of research. The identification of deterministic mutations in the APP, PSEN1, and PSEN2 genes responsible for early-onset autosomal dominant familial forms of AD led to a better understanding of the pathophysiology of th...

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Detalhes bibliográficos
Autor principal: Ertekin-Taner, Nilüfer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874262/
https://ncbi.nlm.nih.gov/pubmed/20236449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt26
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