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Genetics of Alzheimer disease in the pre- and post-GWAS era
Since the 1990s, the genetics of Alzheimer disease (AD) has been an active area of research. The identification of deterministic mutations in the APP, PSEN1, and PSEN2 genes responsible for early-onset autosomal dominant familial forms of AD led to a better understanding of the pathophysiology of th...
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| Format: | Artigo |
| Language: | Inglês |
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BioMed Central
2010
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874262/ https://ncbi.nlm.nih.gov/pubmed/20236449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt26 |
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