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Engineering Metabolism of Chimeric Antigen Receptor (CAR) Cells for Developing Efficient Immunotherapies

SIMPLE SUMMARY: This review paper here describes the recent progress that has been made in chimeric antigen receptor (CAR) -based therapies for treatment of tumors and the role of metabolism in the tumor microenvironment in relation to these therapies. Moreover, this manuscript also discusses role o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Mangal, Joslyn L., Handlos, Jamie L., Esrafili, Arezoo, Inamdar, Sahil, Mcmillian, Sidnee, Wankhede, Mamta, Gottardi, Riccardo, Acharya, Abhinav P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962004/
https://ncbi.nlm.nih.gov/pubmed/33807867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051123
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