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Smart CARs Engineered for Cancer Immunotherapy

PURPOSE: Chimeric antigen receptors (CARs) are synthetic immunoreceptors that can redirect T cells to selectively kill tumor cells, and as “living-drugs” have the potential to generate long-term anti-tumor immunity. Given their recent clinical successes for the treatment of refractory B-cell maligna...

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Detalhes bibliográficos
Publicado no:Curr Opin Oncol
Main Authors: Priceman, Saul J., Forman, Stephen J., Brown, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659816/
https://ncbi.nlm.nih.gov/pubmed/26352543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000232
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