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Smart CARs Engineered for Cancer Immunotherapy

PURPOSE: Chimeric antigen receptors (CARs) are synthetic immunoreceptors that can redirect T cells to selectively kill tumor cells, and as “living-drugs” have the potential to generate long-term anti-tumor immunity. Given their recent clinical successes for the treatment of refractory B-cell maligna...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Curr Opin Oncol
Päätekijät: Priceman, Saul J., Forman, Stephen J., Brown, Christine E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659816/
https://ncbi.nlm.nih.gov/pubmed/26352543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000232
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