Chimeric Antigen Receptor-Engineered T Cells for Immunotherapy of Cancer

CD4(+) and CD8(+) T lymphocytes are powerful components of adaptive immunity, which essentially contribute to the elimination of tumors. Due to their cytotoxic capacity, T cells emerged as attractive candidates for specific immunotherapy of cancer. A promising approach is the genetic modification of...

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Bibliographic Details
Main Authors: Cartellieri, Marc, Bachmann, Michael, Feldmann, Anja, Bippes, Claudia, Stamova, Slava, Wehner, Rebekka, Temme, Achim, Schmitz, Marc
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864912/
https://ncbi.nlm.nih.gov/pubmed/20467460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/956304
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