A Novel Ex Vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells

Genetically engineered T lymphocytes are a promising option for cancer therapy. Prior to adoptive transfer they have to be expanded in vitro to reach therapeutically sufficient numbers. So far, no universal method exists for selective in vitro expansion of engineered T lymphocytes. In order to overc...

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Detalhes bibliográficos
Main Authors: Cartellieri, Marc, Koristka, Stefanie, Arndt, Claudia, Feldmann, Anja, Stamova, Slava, von Bonin, Malte, Töpfer, Katrin, Krüger, Thomas, Geib, Mathias, Michalk, Irene, Temme, Achim, Bornhäuser, Martin, Lindemann, Dirk, Ehninger, Gerhard, Bachmann, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974878/
https://ncbi.nlm.nih.gov/pubmed/24699869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093745
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