A Novel Ex Vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells

Genetically engineered T lymphocytes are a promising option for cancer therapy. Prior to adoptive transfer they have to be expanded in vitro to reach therapeutically sufficient numbers. So far, no universal method exists for selective in vitro expansion of engineered T lymphocytes. In order to overc...

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Autores principales: Cartellieri, Marc, Koristka, Stefanie, Arndt, Claudia, Feldmann, Anja, Stamova, Slava, von Bonin, Malte, Töpfer, Katrin, Krüger, Thomas, Geib, Mathias, Michalk, Irene, Temme, Achim, Bornhäuser, Martin, Lindemann, Dirk, Ehninger, Gerhard, Bachmann, Michael P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974878/
https://ncbi.nlm.nih.gov/pubmed/24699869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093745
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