Fatty Acid Synthase Confers Tamoxifen Resistance to ER+/HER2+ Breast Cancer

SIMPLE SUMMARY: Overactivation of the human epidermal growth factor receptor 2 (HER2) is one of the main drivers of tamoxifen resistance in estrogen receptor (ER)-positive breast cancer patients. Combined targeting of HER2 and ER, however, has yielded disappointing results in the clinical setting. T...

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Udgivet i:Cancers (Basel)
Main Authors: Menendez, Javier A., Papadimitropoulou, Adriana, Vander Steen, Travis, Cuyàs, Elisabet, Oza-Gajera, Bharvi P., Verdura, Sara, Espinoza, Ingrid, Vellon, Luciano, Mehmi, Inderjit, Lupu, Ruth
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961649/
https://ncbi.nlm.nih.gov/pubmed/33800852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051132
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