Heregulin Drives Endocrine Resistance by Altering IL-8 Expression in ER-Positive Breast Cancer

Sustained HER2/HER3 signaling due to the overproduction of the HER3 ligand heregulin (HRG) is proposed as a key contributor to endocrine resistance in estrogen receptor-positive (ER+) breast cancer. The molecular mechanisms linking HER2 transactivation by HRG-bound HER3 to the acquisition of a hormo...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Papadimitropoulou, Adriana, Vellon, Luciano, Atlas, Ella, Steen, Travis Vander, Cuyàs, Elisabet, Verdura, Sara, Espinoza, Ingrid, Menendez, Javier A., Lupu, Ruth
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589856/
https://ncbi.nlm.nih.gov/pubmed/33086721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207737
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