Heregulin Drives Endocrine Resistance by Altering IL-8 Expression in ER-Positive Breast Cancer

Sustained HER2/HER3 signaling due to the overproduction of the HER3 ligand heregulin (HRG) is proposed as a key contributor to endocrine resistance in estrogen receptor-positive (ER+) breast cancer. The molecular mechanisms linking HER2 transactivation by HRG-bound HER3 to the acquisition of a hormo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Papadimitropoulou, Adriana, Vellon, Luciano, Atlas, Ella, Steen, Travis Vander, Cuyàs, Elisabet, Verdura, Sara, Espinoza, Ingrid, Menendez, Javier A., Lupu, Ruth
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Brief Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589856/
https://ncbi.nlm.nih.gov/pubmed/33086721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207737
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