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Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer

Progesterone receptor (PR) isoforms can drive unique phenotypes in luminal breast cancer (BC). Here, we hypothesized that PR-B and PR-A isoforms differentially modify the cross-talk between prolactin and fatty acid synthase (FASN) in BC. We profiled the responsiveness of the FASN gene promoter to pr...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Menendez, Javier A., Peirce, Susan K., Papadimitropoulou, Adriana, Cuyàs, Elisabet, Steen, Travis Vander, Verdura, Sara, Vellon, Luciano, Chen, Wen Y., Lupu, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803566/
https://ncbi.nlm.nih.gov/pubmed/33335078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202289
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