The zinc-binding domain of mammalian prolyl-tRNA synthetase is indispensable for catalytic activity and organism viability

Aminoacyl-tRNA synthetases (AARS) participate in decoding the genome by catalyzing conjugation of amino acids to their cognate tRNAs. During evolution, biochemical and environmental conditions markedly influenced the sequence and structure of the 20 AARSs, revealing adaptations dictating canonical a...

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Detaylı Bibliyografya
Yayımlandı:iScience
Asıl Yazarlar: Vasu, Kommireddy, Ramachandiran, Iyappan, Terenzi, Fulvia, Khan, Debjit, China, Arnab, Khan, Krishnendu, Chechi, Aayushi, Baleanu-Gogonea, Camelia, Gogonea, Valentin, Fox, Paul L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960942/
https://ncbi.nlm.nih.gov/pubmed/33748704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102215
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