Structural control of caspase-generated glutamyl-tRNA synthetase by appended noncatalytic WHEP domains

Aminoacyl-tRNA synthetases are ubiquitous, evolutionarily conserved enzymes catalyzing the conjugation of amino acids onto cognate tRNAs. During eukaryotic evolution, tRNA synthetases have been the targets of persistent structural modifications. These modifications can be additive, as in the evoluti...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Halawani, Dalia, Gogonea, Valentin, DiDonato, Joseph A., Pipich, Vitaliy, Yao, Peng, China, Arnab, Topbas, Celalettin, Vasu, Kommireddy, Arif, Abul, Hazen, Stanley L., Fox, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995526/
https://ncbi.nlm.nih.gov/pubmed/29643180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807503
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