Inhibition of neuroinflammatory nitric oxide signaling suppresses glycation and prevents neuronal dysfunction in mouse prion disease

Several neurodegenerative diseases associated with protein misfolding (Alzheimer’s and Parkinson’s disease) exhibit oxidative and nitrergic stress following initiation of neuroinflammatory pathways. Associated nitric oxide (NO)-mediated posttranslational modifications impact upon protein functions t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Bourgognon, Julie-Myrtille, Spiers, Jereme G., Robinson, Sue W., Scheiblich, Hannah, Glynn, Paul, Ortori, Catharine, Bradley, Sophie J., Tobin, Andrew B., Steinert, Joern R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958397/
https://ncbi.nlm.nih.gov/pubmed/33653950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009579118
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