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Boronic acid with high oxidative stability and utility in biological contexts

Despite their desirable attributes, boronic acids have had a minimal impact in biological contexts. A significant problem has been their oxidative instability. At physiological pH, phenylboronic acid and its boronate esters are oxidized by reactive oxygen species at rates comparable to those of thio...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Graham, Brian J., Windsor, Ian W., Gold, Brian, Raines, Ronald T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958229/
https://ncbi.nlm.nih.gov/pubmed/33653951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013691118
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