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Boronate-Mediated Biologic Delivery

[Image: see text] Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids readily form boronate esters with the 1,2- and 1,3-diols of saccharides, such as those that coat the surface of mammalian cells. Here pendant boronic acids are shown to enhance the cytosolic d...

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Detalhes bibliográficos
Main Authors: Ellis, Gregory A., Palte, Michael J., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304437/
https://ncbi.nlm.nih.gov/pubmed/22303837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210719s
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