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Boronate-Mediated Biologic Delivery
[Image: see text] Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids readily form boronate esters with the 1,2- and 1,3-diols of saccharides, such as those that coat the surface of mammalian cells. Here pendant boronic acids are shown to enhance the cytosolic d...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304437/ https://ncbi.nlm.nih.gov/pubmed/22303837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210719s |
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